Maad Rayan Publishing Company Biomedical Research Bulletin 2980-9924 2 1 2024 03 29 A Pharmacological Look at Neuroinflammation: Focusing on the Natural Remedies 45 48 10.34172/biomedrb.2024.07 EN Kiarash Fekri https://orcid.org/0000-0002-1982-8743 Yalda Alizadeh Mahdi Alizadeh Soufilar Amir Shadabi Hadiseh Alizadeh Shirsavar REVIEW 10.34172/biomedrb.2024.07 2024 03 05 2024 03 19 Neuroinflammation (NI) is defined as a condition in which neurons undergo inflammatory processes, which can lead to transient and permanent functional disruptions in neurons. These disruptions can initiate various neuropsychiatric conditions such as Alzheimer’s and Parkinson’s diseases. Significant findings have been reported regarding the underlying conditions such as infections and oxidative stress that contribute to neuronal inflammation in recent years. As such, studies have introduced many valuable approaches to alleviate NI and its subsequent medical conditions. Pharmacological approaches have long been of interest to patients and therapists, particularly in the context of NI, where significant achievements have been made. Scrutinizing the literature indicates that natural remedies have gained considerable attention among researchers in this regard. Therefore, the current review was conducted to collect and classify relevant studies to provide reliable information on the role of natural remedies in NI management.