Abstract
Background: Breast cancer is one of the most common types of cancer worldwide, and long non-coding RNAs (lncRNAs) have been implicated in its development and progression.
Materials: In this study, we investigated the expression of BRAF-activated non-coding RNA (BANCR) in tumor tissues and adjacent non-tumor tissues of 123 breast cancer patients.
Results: Our results showed that the expression of BANCR was significantly higher in tumor tissues compared to adjacent non-tumor tissues. Based on the results, the mean fold change was 7.894 (P < 0.001). Moreover, the result revealed that the expression of BANCR was increased in patients with lymph node invasion in comparison to patients without lymph node invasion (LogFC = 1.358, P < 0.001).
Conclusion: The study findings suggest that BANCR may be a potential biomarker for breast cancer; however, further research is needed to confirm these results.