Kiarash Fekri
1,2* 
, Yalda Alizadeh
3, Mahdi Alizadeh Soufilar
3, Amir Shadabi
4, Hadiseh Alizadeh Shirsavar
31 Preclinical Department, Amol Campus of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
2 Department of Paramedicine, Amol School of Paramedicine, Mazandaran University of Medical Sciences, Sari, Iran
3 Department of Nursing, Amol School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran
4 Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
Abstract
Neuroinflammation (NI) is defined as a condition in which neurons undergo inflammatory processes, which can lead to transient and permanent functional disruptions in neurons. These disruptions can initiate various neuropsychiatric conditions such as Alzheimer’s and Parkinson’s diseases. Significant findings have been reported regarding the underlying conditions such as infections and oxidative stress that contribute to neuronal inflammation in recent years. As such, studies have introduced many valuable approaches to alleviate NI and its subsequent medical conditions. Pharmacological approaches have long been of interest to patients and therapists, particularly in the context of NI, where significant achievements have been made. Scrutinizing the literature indicates that natural remedies have gained considerable attention among researchers in this regard. Therefore, the current review was conducted to collect and classify relevant studies to provide reliable information on the role of natural remedies in NI management.